Syngenta Settles Paraquat Lawsuits Tied to Parkinson’s Risk

Timothy Gocklin, MBA, MSF Editor in Chief

By Editor-in-Chief, Timothy Gocklin, MBA, MSF

Syngenta Tackles Resolution of Thousands of Paraquat Cases with Parkinson’s Disease Allegations



Background: The Paraquat Controversy

Paraquat, a highly toxic herbicide first synthesized in the 1960s, has been widely used in agriculture to destroy weeds and grasses. While very effective, exposure to paraquat can have serious health consequences. Numerous scientific studies over many years have linked paraquat exposure to an increased risk of developing Parkinson’s disease, a progressive neurodegenerative disorder with symptoms of tremors, rigidity, and motor control.

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Paraquat is a “restricted use” pesticide in the United States, meaning that it can only be applied by certified applicators. Yet despite this, there have been persistent worries about the adequacy of safety measures and potential exposure for farm workers and nearby residents. 


The Litigation Landscape

Through April of 2025, Syngenta is fighting over 5,800 lawsuits that are consolidated in multidistrict litigation (MDL) in the Southern District of Illinois U.S. District Court. In addition to that, there are over 450 cases pending in California state courts, and numerous others have been filed across various jurisdictions. The plaintiffs have alleged that Syngenta failed to warn users of the risks of paraquat, namely its alleged link to Parkinson’s disease.

The lawsuit has been marked by complex legal battles over scientific testimony. In 2024, a federal judge excluded testimony from the lead expert witness for the plaintiffs on general causation, citing concerns about the reliability of the methodology used to conclude a connection between paraquat and Parkinson’s disease. The ruling led to the dismissal of several bellwether cases and posed significant challenges to the plaintiffs in the future. 


The Settlement Agreement

On April 14, 2025, Syngenta and plaintiffs’ lead counsel released a signed letter of agreement intended to resolve a significant percentage of the pending cases. While no terms of the settlement have been released, the agreement is reportedly resolving most of the cases in the federal MDL and perhaps some in state court. The terms of the settlement are due to be resolved within 30 days. 

Syngenta contends that the settlement is not an admission of liability or acknowledgment that paraquat causes Parkinson’s disease. In a statement, the company claimed that “decades of scientific research and regulatory reviews have not established a causal link between paraquat and Parkinson’s disease.” Syngenta did concede, however, that prolonged litigation is costly and distracting, and it chose to pursue a settlement. Naturally, this development coincides with discussions surrounding the 2025 Federal Budget.


Reactions and Implications

The settlement has received mixed reactions. Some lawyers for the plaintiffs, particularly those who represented clients outside the MDL, felt shortchanged and complained of exclusion from the negotiation process. There have been concerns regarding unequal treatment of the plaintiffs and lack of transparency regarding settlement. 

The settlement further fuels argument on how paraquat is regulated in America. Even though the chemical is banned in over 60 countries due to fears over its health effects, the country is still using it. Tighter control of pesticides demands that tighter controls of pesticides are being advocated for since the settlement calls for the re-examination of the safety and approval process of hazardous chemicals. This is part of the broader discussion seen in the 2025 Federal Budget deliberations.


Looking Ahead

Resolution of the lawsuits will have far-reaching implications for the agricultural industry and the body of law surrounding chemical exposure claims. For Syngenta, the settlement will be likely to serve to assist in mitigating ongoing legal expenses and reputational harm. For plaintiffs, it is a potential path for compensation, though the reasonableness of the settlement amounts remains a matter of dispute.

As the final terms of the settlement are resolved and implemented, focus will likely shift to the broader implications for pesticide regulation, occupational safety, and corporate responsibility. The paraquat litigation serves as a reminder of the delicate dance between science, law, and public health in addressing the risks of industrial chemicals. Additionally, the implications of the settlement may very well inform future allocations within the discussions of 2025 Federal Budget.

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